Flurazepam brief description:

Flurazepam is categorized as a axial afraid arrangement sedative/hypnotic (tranquilizer). It belongs to a chic of drugs accepted as benzodiazepines, which are the a lot of broadly assigned medications that affect axial afraid arrangement function. Flurazepam hydrochloride is rapidly captivated from the G.I. tract. Flurazepam is rapidly metabolized in the alarmist and is excreted primarily in the urine. Peak flurazepam claret concentrations action at 30 to 60 account post-dosing. The harmonic beggarly credible half-life (the time it takes to annihilate bisected of the biologic from the claret stream) of flurazepam is 2.3 hours. The N1-hydroxyethyl-flurazepam was assessable alone during the aboriginal hours afterwards a 30 mg dosage and was not apparent afterwards 24 hours. The above metabolite in claret was N1-desalkyl-flurazepam which accomplished steady-state (plateau) levels afterwards 7 to 10 canicule of dosing, at levels about five- to sixfold greater than the 24-hour levels empiric on Day 1. The half-life of abolishment of N1-desalkyl-flurazepam ranged from 47 to 100 hours. The above urinary metabolite is conjugated N1-hydroxyethyl-flurazepam which accounts for 22 to 55 percent of the dose. Less than 1% of the dosage is excreted in the urine as N1-desalkyl-flurazepam.