Chloroxine is a constructed antibacterial
admixture that is able in the analysis of dandruff and seborrheic dermatitis if
congenital in a shampoo. It is a halogenated hydroxyquinoline with
antibacterial and antifungal backdrop agnate to those of clioquinol. It is
acclimated topically in the analysis of dandruff and seborrhoeic dermatitis of
the scalp. It has aswell been accustomed orally in affairs for gastrointestinal
disorders. It is a basic of halquinol.
Chloroxine has an antibacterial action,
inhibiting the advance of gram-positive as able-bodied as some gram-negative
organisms. Also, chloroxine has apparent some antifungal action adjoin
assertive dermatophytes and yeasts.
Although the apparatus of action is not
understood, chloroxine may apathetic down mitotic action in the epidermis,
thereby abbreviation boundless ascent associated with dandruff or seborrheic
dermatitis of the scalp. Chloroxine induces SOS-DNA adjustment in E. coli, so
chloroxine may be genotoxic to bacteria.
Chloroxine is a constructed antibacterial
compound. Chloroxine is a admixture acclimated in some shampoos for the
analysis of dandruff and seborrheic dermatitis of the scalp.
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