CAS:
108321-42-2
Molecular
Formula: C20H42N4O14S
Molecular
weight:594.63
Geneticin,
generally aswell alleged G418, is an aminoglycoside antibacterial that inhibits
protein amalgam in beastly beef by interfering with ribosomal function.
Geneticin is an aminoglycoside antibacterial agnate in anatomy to gentamicin
B1. It is produced by Micromonospora rhodorangea. Geneticin blocks polypeptide
amalgam by inhibiting the addendum footfall in both prokaryotic and eukaryotic
cells. Resistance to Geneticin is conferred by the neo gene from Tn5 encoding
an aminoglycoside 3‘-phosphotransferase, APH 3‘ II. Geneticin is frequently
used in class analysis to baddest genetically engineered cells.
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