Unlike erythromycin, telithromycin is acid-stable and can accordingly be
taken orally while getting adequate from belly acids. It is adequately rapidly
absorbed, and diffused into a lot of tissues and phagocytes. Due to the top
absorption in phagocytes, telithromycin is actively transported to the website
of infection. During alive phagocytosis, ample concentrations of telithromycin
is released. The absorption of telithromycin in the tissues is abundant college
than in plasma.Telithromycin fulfills a role that has arisen due to the
acceleration of microbial attrition to absolute macrolides and appears to be
able adjoin macrolide-resistant Streptococcus pneumoniae. The defining
appropriate appropriate of the ketolides as against to added macrolides is the
abatement of the aloof sugar, L-cladinose from the 3 position of the macrolide
ring and the consecutive blaze of the 3-hydroxyl to a 3-keto anatomic group.
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